The Lord very commonly changes our plans, for He loves to surprise. Think Enoch, Noah, Abraham, Joseph, etc... Are you doing what you thought you'd be doing five years ago? Are you where you thought you would be? In most cases probably not. Why? God moved in and your plans had to go.
What IS important in the day by day is why and how I go about life. These two answers will describe much of who I am and what others see me as. Is knowing God at the top of my interests? Is glorifying Him my first goal? Is drawing close to His secret place my highest priority?
And I mean literally.
If so, my attitudes and actions will be what they ought to be. I can pursue my plans, within reason, but if they are moved aside by the divine hand, my philosophy will keep me perfectly on track for God's blessing.
You know why? In part, because those plans won't dominate my horizon nor will the selfish drive to accomplish them be there to hurt others along the way. "Seek ye first ..." (Mt. 6:33) is a simple, safe, and sure way to satisfaction and contentment.